A Functional 3′UTR Polymorphism (rs2235749) of Prodynorphin Alters microRNA-365 Binding in Ventral Striatonigral Neurons to Influence Novelty Seeking and Positive Reward Traits

Genetic factors impact behavioral traits relevant to numerous psychiatric disorders and risk-taking behaviors, and different lines of evidence have indicated that discrete neurobiological systems contribute to such individual differences. In this study, we explored the relationship of genetic varian...

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Vydáno v:Neuropsychopharmacology
Hlavní autoři: Egervari, Gabor, Jutras-Aswad, Didier, Landry, Joseph, Miller, Michael L, Anderson, Sarah Ann, Michaelides, Michael, Jacobs, Michelle M, Peter, Cyril, Yiannoulos, Georgia, Liu, Xun, Hurd, Yasmin L
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Original Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987849/
https://ncbi.nlm.nih.gov/pubmed/27074815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/npp.2016.53
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