Impaired periamygdaloid-cortex prodynorphin is characteristic of opiate addiction and depression

Negative affect is critical for conferring vulnerability to opiate addiction as reflected by the high comorbidity of opiate abuse with major depressive disorder (MDD). Rodent models implicate amygdala prodynorphin (Pdyn) as a mediator of negative affect; however, evidence of PDYN involvement in huma...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Anderson, Sarah Ann R., Michaelides, Michael, Zarnegar, Parisa, Ren, Yanhua, Fagergren, Pernilla, Thanos, Panayotis K., Wang, Gene-Jack, Bannon, Michael, Neumaier, John F., Keller, Eva, Volkow, Nora D., Hurd, Yasmin L.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Clinical Investigation 2013
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859405/
https://ncbi.nlm.nih.gov/pubmed/24231353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70395
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