Impaired periamygdaloid-cortex prodynorphin is characteristic of opiate addiction and depression

Negative affect is critical for conferring vulnerability to opiate addiction as reflected by the high comorbidity of opiate abuse with major depressive disorder (MDD). Rodent models implicate amygdala prodynorphin (Pdyn) as a mediator of negative affect; however, evidence of PDYN involvement in huma...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Anderson, Sarah Ann R., Michaelides, Michael, Zarnegar, Parisa, Ren, Yanhua, Fagergren, Pernilla, Thanos, Panayotis K., Wang, Gene-Jack, Bannon, Michael, Neumaier, John F., Keller, Eva, Volkow, Nora D., Hurd, Yasmin L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Clinical Investigation 2013
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3859405/
https://ncbi.nlm.nih.gov/pubmed/24231353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI70395
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