Complete in vitro generation of fertile oocytes from mouse primordial germ cells

Reconstituting gametogenesis in vitro is a key goal for reproductive biology and regenerative medicine. Successful in vitro reconstitution of primordial germ cells and spermatogenesis has recently had a significant effect in the field. However, recapitulation of oogenesis in vitro remains unachieved...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Morohaku, Kanako, Tanimoto, Ren, Sasaki, Keisuke, Kawahara-Miki, Ryouka, Kono, Tomohiro, Hayashi, Katsuhiko, Hirao, Yuji, Obata, Yayoi
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987791/
https://ncbi.nlm.nih.gov/pubmed/27457928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1603817113
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