Immunoproteasome dysfunction augments alternative polarization of alveolar macrophages

The proteasome is a central regulatory hub for intracellular signaling by degrading numerous signaling mediators. Immunoproteasomes are specialized types of proteasomes involved in shaping adaptive immune responses, but their role in innate immune signaling is still elusive. Here, we analyzed immuno...

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Publicat a:Cell Death Differ
Autors principals: Chen, S, Kammerl, I E, Vosyka, O, Baumann, T, Yu, Y, Wu, Y, Irmler, M, Overkleeft, H S, Beckers, J, Eickelberg, O, Meiners, S, Stoeger, T
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2016
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Original Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987736/
https://ncbi.nlm.nih.gov/pubmed/26990663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.3
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