Immunoproteasome dysfunction augments alternative polarization of alveolar macrophages

The proteasome is a central regulatory hub for intracellular signaling by degrading numerous signaling mediators. Immunoproteasomes are specialized types of proteasomes involved in shaping adaptive immune responses, but their role in innate immune signaling is still elusive. Here, we analyzed immuno...

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Detalhes bibliográficos
Publicado no:Cell Death Differ
Main Authors: Chen, S, Kammerl, I E, Vosyka, O, Baumann, T, Yu, Y, Wu, Y, Irmler, M, Overkleeft, H S, Beckers, J, Eickelberg, O, Meiners, S, Stoeger, T
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987736/
https://ncbi.nlm.nih.gov/pubmed/26990663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2016.3
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