ΔNp63 regulates IL-33 and IL-31 signaling in atopic dermatitis

Atopic dermatitis (AD) is the most common inflammatory skin disease with no well-delineated cause or effective cure. Here we show that the p53 family member p63, specifically the ΔNp63, isoform has a key role in driving keratinocyte activation in AD. We find that overexpression of ΔNp63 in transgeni...

Description complète

Enregistré dans:
Détails bibliographiques
Publié dans:Cell Death Differ
Auteurs principaux: Rizzo, J M, Oyelakin, A, Min, S, Smalley, K, Bard, J, Luo, W, Nyquist, J, Guttman-Yassky, E, Yoshida, T, De Benedetto, A, Beck, L A, Sinha, S, Romano, R-A
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Original Paper
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987726/
https://ncbi.nlm.nih.gov/pubmed/26768665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2015.162
Tags: Ajouter un tag
Pas de tags, Soyez le premier à ajouter un tag!

Documents similaires