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Ignavine: a novel allosteric modulator of the μ opioid receptor

Processed Aconiti tuber (PAT) is used to treat pain associated with various disorders. Although it has been demonstrated that the κ opioid receptor (KOR) signaling pathway is a mediator of the analgesic effect of PAT, active components affecting opioid signaling have not yet been identified. In this...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ohbuchi, Katsuya, Miyagi, Chika, Suzuki, Yasuyuki, Mizuhara, Yasuharu, Mizuno, Keita, Omiya, Yuji, Yamamoto, Masahiro, Warabi, Eiji, Sudo, Yuka, Yokoyama, Akinobu, Miyano, Kanako, Hirokawa, Takatsugu, Uezono, Yasuhito
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987652/
https://ncbi.nlm.nih.gov/pubmed/27530869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep31748
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