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A Toll receptor–FoxO pathway represses Pavarotti/MKLP1 to promote microtubule dynamics in motoneurons

FoxO proteins are evolutionarily conserved regulators of neuronal structure and function, yet the neuron-specific pathways within which they act are poorly understood. To elucidate neuronal FoxO function in Drosophila melanogaster, we first screened for FoxO’s upstream regulators and downstream effe...

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Detalles Bibliográficos
Publicado en:J Cell Biol
Main Authors: McLaughlin, Colleen N., Nechipurenko, Inna V., Liu, Nan, Broihier, Heather T.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987293/
https://ncbi.nlm.nih.gov/pubmed/27502486
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201601014
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