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Polymerase independent repression of FoxO1 transcription by sequence-specific PARP1 binding to FoxO1 promoter
Poly(ADP-ribose) polymerase 1 (PARP1) regulates gene transcription in addition to functioning as a DNA repair factor. Forkhead box O1 (FoxO1) is a transcription factor involved in extensive biological processes. Here, we report that PARP1 binds to two separate motifs on the FoxO1 promoter and repres...
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| Publicado no: | Cell Death Dis |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6987093/ https://ncbi.nlm.nih.gov/pubmed/31992690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-020-2265-y |
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