Direct Transcriptional Consequences of Somatic Mutation in Breast Cancer

Disordered transcriptomes of cancer encompass direct effects of somatic mutation on transcription, coordinated secondary pathway alterations, and increased transcriptional noise. To catalog the rules governing how somatic mutation exerts direct transcriptional effects, we developed an exhaustive pip...

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Gepubliceerd in:Cell Rep
Hoofdauteurs: Shlien, Adam, Raine, Keiran, Fuligni, Fabio, Arnold, Roland, Nik-Zainal, Serena, Dronov, Serge, Mamanova, Lira, Rosic, Andrej, Ju, Young Seok, Cooke, Susanna L., Ramakrishna, Manasa, Papaemmanuil, Elli, Davies, Helen R., Tarpey, Patrick S., Van Loo, Peter, Wedge, David C., Jones, David R., Martin, Sancha, Marshall, John, Anderson, Elizabeth, Hardy, Claire, Barbashina, Violetta, Aparicio, Samuel A.J.R., Sauer, Torill, Garred, Øystein, Vincent-Salomon, Anne, Mariani, Odette, Boyault, Sandrine, Fatima, Aquila, Langerød, Anita, Borg, Åke, Thomas, Gilles, Richardson, Andrea L., Børresen-Dale, Anne-Lise, Polyak, Kornelia, Stratton, Michael R., Campbell, Peter J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Cell Press 2016
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987284/
https://ncbi.nlm.nih.gov/pubmed/27498871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.07.028
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