CpG Methylation Analysis of HPV16 in Laser Capture Microdissected Archival Tissue and Whole Tissue Sections from High Grade Anal Squamous Intraepithelial Lesions: A Potential Disease Biomarker

Incidence and mortality rates of anal cancer are increasing globally. More than 90% of anal squamous cell carcinomas (ASCC) are associated with human papillomavirus (HPV). Studies on HPV-related anogenital lesions have shown that patterns of methylation of viral and cellular DNA targets could potent...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Molano, Monica, Tabrizi, Sepehr N., Garland, Suzanne M., Roberts, Jennifer M., Machalek, Dorothy A., Phillips, Samuel, Chandler, David, Hillman, Richard J., Grulich, Andrew E., Jin, Fengyi, Poynten, I. Mary, Templeton, David J., Cornall, Alyssa M.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987059/
https://ncbi.nlm.nih.gov/pubmed/27529629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160673
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