Laser capture microdissection as a tool to evaluate human papillomavirus genotyping and methylation as biomarkers of persistence and progression of anal lesions

INTRODUCTION: Anal squamous cell carcinoma is preceded by persistent infection with high-risk human papillomavirus (HPV) and the cancer precursor, high-grade squamous intraepithelial lesion (HSIL). Detection of specific HPV genotypes and HPV-related biomarkers may be an option for primary anal scree...

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Detalhes bibliográficos
Publicado no:BMJ Open
Main Authors: Cornall, Alyssa M, Roberts, Jennifer M, Molano, Monica, Machalek, Dorothy A, Phillips, Samuel, Hillman, Richard J, Grulich, Andrew E, Jin, Fengyi, Poynten, I Mary, Templeton, David J, Garland, Suzanne M, Tabrizi, Sepehr N
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2015
Assuntos:
Research Methods
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4554896/
https://ncbi.nlm.nih.gov/pubmed/26310402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/bmjopen-2015-008439
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