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Precise Detection of IDH1/2 and BRAF Hotspot Mutations in Clinical Glioma Tissues by a Differential Calculus Analysis of High-Resolution Melting Data

High resolution melting (HRM) is a simple and rapid method for screening mutations. It offers various advantages for clinical diagnostic applications. Conventional HRM analysis often yields equivocal results, especially for surgically obtained tissues. We attempted to improve HRM analyses for more e...

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發表在:PLoS One
Main Authors: Hatae, Ryusuke, Hata, Nobuhiro, Yoshimoto, Koji, Kuga, Daisuke, Akagi, Yojiro, Murata, Hideki, Suzuki, Satoshi O., Mizoguchi, Masahiro, Iihara, Koji
格式: Artigo
語言:Inglês
出版: Public Library of Science 2016
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987040/
https://ncbi.nlm.nih.gov/pubmed/27529619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160489
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