Precise Detection of IDH1/2 and BRAF Hotspot Mutations in Clinical Glioma Tissues by a Differential Calculus Analysis of High-Resolution Melting Data

High resolution melting (HRM) is a simple and rapid method for screening mutations. It offers various advantages for clinical diagnostic applications. Conventional HRM analysis often yields equivocal results, especially for surgically obtained tissues. We attempted to improve HRM analyses for more e...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hatae, Ryusuke, Hata, Nobuhiro, Yoshimoto, Koji, Kuga, Daisuke, Akagi, Yojiro, Murata, Hideki, Suzuki, Satoshi O., Mizoguchi, Masahiro, Iihara, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987040/
https://ncbi.nlm.nih.gov/pubmed/27529619
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0160489
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