Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients

Circulating cell-free DNA (cfDNA) released from cancerous tissues has been found to harbor tumor-associated alterations and to represent the molecular composition of the tumor. Recent advances in technologies, especially in next-generation sequencing, enable the analysis of low amounts of cfDNA from...

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Udgivet i:PLoS One
Main Authors: Dietz, Steffen, Schirmer, Uwe, Mercé, Clémentine, von Bubnoff, Nikolas, Dahl, Edgar, Meister, Michael, Muley, Thomas, Thomas, Michael, Sültmann, Holger
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2016
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4987014/
https://ncbi.nlm.nih.gov/pubmed/27529345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161012
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