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Structure–function analysis and genetic interactions of the SmG, SmE, and SmF subunits of the yeast Sm protein ring

A seven-subunit Sm protein ring forms a core scaffold of the U1, U2, U4, and U5 snRNPs that direct pre-mRNA splicing. Using human snRNP structures to guide mutagenesis in Saccharomyces cerevisiae, we gained new insights into structure–function relationships of the SmG, SmE, and SmF subunits. An alan...

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Podrobná bibliografie
Vydáno v:RNA
Hlavní autoři: Schwer, Beate, Kruchten, Joshua, Shuman, Stewart
Médium: Artigo
Jazyk:Inglês
Vydáno: Cold Spring Harbor Laboratory Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986888/
https://ncbi.nlm.nih.gov/pubmed/27417296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.057448.116
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