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Tropomodulin 1 Regulation of Actin Is Required for the Formation of Large Paddle Protrusions Between Mature Lens Fiber Cells

PURPOSE: To elucidate the proteins required for specialized small interlocking protrusions and large paddle domains at lens fiber cell tricellular junctions (vertices), we developed a novel method to immunostain single lens fibers and studied changes in cell morphology due to loss of tropomodulin 1...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Cheng, Catherine, Nowak, Roberta B., Biswas, Sondip K., Lo, Woo-Kuen, FitzGerald, Paul G., Fowler, Velia M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986768/
https://ncbi.nlm.nih.gov/pubmed/27537257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.16-19949
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