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Tropomodulin1 is required for membrane skeleton organization and hexagonal geometry of fiber cells in the mouse lens

Hexagonal packing geometry is a hallmark of close-packed epithelial cells in metazoans. Here, we used fiber cells of the vertebrate eye lens as a model system to determine how the membrane skeleton controls hexagonal packing of post-mitotic cells. The membrane skeleton consists of spectrin tetramers...

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Detalhes bibliográficos
Main Authors: Nowak, Roberta B., Fischer, Robert S., Zoltoski, Rebecca K., Kuszak, Jerome R., Fowler, Velia M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753162/
https://ncbi.nlm.nih.gov/pubmed/19752024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200905065
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