The ciliary GTPase Arl13b regulates cell migration and cell cycle progression

The GTPase ARL13B is localized to primary cilia; small cellular protrusions that act as antennae. Its defective ARL13B hennin (HNN) variant is linked causally with Joubert Syndrome, a developmental ciliopathy attributed to poor sensing of extracellular chemical gradients. We tested the hypothesis th...

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Bibliografiske detaljer
Udgivet i:Cell Adh Migr
Main Authors: Pruski, Michal, Rajnicek, Ann, Yang, Zhifu, Clancy, Hannah, Ding, Yu-Qiang, McCaig, Colin D., Lang, Bing
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2016
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Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986708/
https://ncbi.nlm.nih.gov/pubmed/26963749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/19336918.2016.1159380
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