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Role of tyrosine-kinase inhibitors in myeloproliferative neoplasms: comparative lessons learned
An important pathogenetic distinction in the classification of myeloproliferative neoplasms (MPNs) is the presence or absence of the BCR–ABL fusion gene, which encodes a unique oncogenic tyrosine kinase. The BCR–ABL fusion, caused by the formation of the Philadelphia chromosome (Ph) through transloc...
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| Publicado no: | Onco Targets Ther |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Dove Medical Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4986686/ https://ncbi.nlm.nih.gov/pubmed/27570458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S102504 |
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