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Changes in insulin and insulin signaling in Alzheimer’s disease: cause or consequence?
Individuals with type 2 diabetes have an increased risk for developing Alzheimer’s disease (AD), although the causal relationship remains poorly understood. Alterations in insulin signaling (IS) are reported in the AD brain. Moreover, oligomers/fibrils of amyloid-β (Aβ) can lead to neuronal insulin...
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| Publicado en: | J Exp Med |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Rockefeller University Press
2016
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4986537/ https://ncbi.nlm.nih.gov/pubmed/27432942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20160493 |
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