A hypofractionated radiation regimen avoids the lymphopenia associated with neoadjuvant chemoradiation therapy of borderline resectable and locally advanced pancreatic adenocarcinoma

BACKGROUND: Preclinical studies have shown synergy between radiation therapy and immunotherapy. However, in almost all preclinical models, radiation is delivered in single doses or short courses of high doses (hypofractionated radiation). By contrast in most clinical settings, radiation is delivered...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunother Cancer
Prif Awduron: Crocenzi, Todd, Cottam, Benjamin, Newell, Pippa, Wolf, Ronald F., Hansen, Paul D., Hammill, Chet, Solhjem, Matthew C., To, Yue-Yun, Greathouse, Amy, Tormoen, Garth, Jutric, Zeljka, Young, Kristina, Bahjat, Keith S., Gough, Michael J., Crittenden, Marka R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2016
Pynciau:
Research Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986363/
https://ncbi.nlm.nih.gov/pubmed/27532020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-016-0149-6
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