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Mechanisms of tumor escape in the context of the T-cell-inflamed and the non-T-cell-inflamed tumor microenvironment

Checkpoint blockade therapy has been proven to be highly active across many cancer types but emerging evidence indicates that the therapeutic benefit is limited to a subset of patients in each cancer entity. The presence of CD8(+) T cells within the tumor microenvironment or the invasive margin of t...

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Vydáno v:Int Immunol
Hlavní autor: Spranger, Stefani
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986232/
https://ncbi.nlm.nih.gov/pubmed/26989092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/intimm/dxw014
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