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CSC-3436 switched tamoxifen-induced autophagy to apoptosis through the inhibition of AMPK/mTOR pathway
BACKGROUND: Triple-negative breast cancer (TNBC) lacks specific therapeutic target and limits to chemotherapy and is essential to develop novel therapeutic regimens. Increasing studies indicated that tamoxifen, a selective estrogen receptor modulators (SERMs), has anti-tumor therapeutic effect in es...
Αποθηκεύτηκε σε:
| Τόπος έκδοσης: | J Biomed Sci |
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| Κύριοι συγγραφείς: | , , , , , , |
| Μορφή: | Artigo |
| Γλώσσα: | Inglês |
| Έκδοση: |
BioMed Central
2016
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| Θέματα: | |
| Διαθέσιμο Online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4986227/ https://ncbi.nlm.nih.gov/pubmed/27526942 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12929-016-0275-y |
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