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Design and In-vitro Evaluation of Sustained Release Floating Tablets of Metformin HCl Based on Effervescence and Swelling

An oral sustained-release floating tablet formulation of metformin HCl was designed and developed. Effervescence and swelling properties were attributed on the developed tablets by sodium bicarbonate and HPMC-PEO polymer combination, respectively. Tablet composition was optimized by response surface...

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Dettagli Bibliografici
Pubblicato in:Iran J Pharm Res
Autori principali: Senjoti, Faria Gias, Mahmood, Syed, Jaffri, Juliana Md, Mandal, Uttam Kumar
Natura: Artigo
Lingua:Inglês
Pubblicazione: Shaheed Beheshti University of Medical Sciences 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4986121/
https://ncbi.nlm.nih.gov/pubmed/27610147
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