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The N-terminal tropomyosin- and actin-binding sites are important for leiomodin 2’s function
Leiomodin is a potent actin nucleator related to tropomodulin, a capping protein localized at the pointed end of the thin filaments. Mutations in leiomodin-3 are associated with lethal nemaline myopathy in humans, and leiomodin-2–knockout mice present with dilated cardiomyopathy. The arrangement of...
Tallennettuna:
| Julkaisussa: | Mol Biol Cell |
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| Päätekijät: | , , , , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
The American Society for Cell Biology
2016
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4985258/ https://ncbi.nlm.nih.gov/pubmed/27307584 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E16-03-0200 |
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