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Transcriptionally regulated and nontoxic delivery of the hyperactive Sleeping Beauty Transposase
The Sleeping Beauty (SB) transposase and, in particular, its hyperactive variant SB100X raises increasing interest for gene therapy application, including genome modification and, more recently, induced pluripotent stem cells (iPS) reprogramming. The documented cytotoxicity of the transposase, when...
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| Pubblicato in: | Mol Ther Methods Clin Dev |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4985251/ https://ncbi.nlm.nih.gov/pubmed/27574698 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mtm.2016.38 |
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