Self-Amplifying mRNA Vaccines Expressing Multiple Conserved Influenza Antigens Confer Protection against Homologous and Heterosubtypic Viral Challenge

Current hemagglutinin (HA)-based seasonal influenza vaccines induce vaccine strain-specific neutralizing antibodies that usually fail to provide protection against mismatched circulating viruses. Inclusion in the vaccine of highly conserved internal proteins such as the nucleoprotein (NP) and the ma...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:PLoS One
Main Authors: Magini, Diletta, Giovani, Cinzia, Mangiavacchi, Simona, Maccari, Silvia, Cecchi, Raffaella, Ulmer, Jeffrey B., De Gregorio, Ennio, Geall, Andrew J., Brazzoli, Michela, Bertholet, Sylvie
פורמט: Artigo
שפה:Inglês
יצא לאור: Public Library of Science 2016
נושאים:
Research Article
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985159/
https://ncbi.nlm.nih.gov/pubmed/27525409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161193
תגים: הוספת תג
אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!

פריטים דומים