COPD Exacerbation Biomarkers Validated Using Multiple Reaction Monitoring Mass Spectrometry

BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) result in considerable morbidity and mortality. However, there are no objective biomarkers to diagnose AECOPD. METHODS: We used multiple reaction monitoring mass spectrometry to quantify 129 distinct proteins in plasma...

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Pubblicato in:PLoS One
Autori principali: Leung, Janice M., Chen, Virginia, Hollander, Zsuzsanna, Dai, Darlene, Tebbutt, Scott J., Aaron, Shawn D., Vandemheen, Kathy L., Rennard, Stephen I., FitzGerald, J. Mark, Woodruff, Prescott G., Lazarus, Stephen C., Connett, John E., Coxson, Harvey O., Miller, Bruce, Borchers, Christoph, McManus, Bruce M., Ng, Raymond T., Sin, Don D.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985129/
https://ncbi.nlm.nih.gov/pubmed/27525416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161129
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