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COPD Exacerbation Biomarkers Validated Using Multiple Reaction Monitoring Mass Spectrometry

BACKGROUND: Acute exacerbations of chronic obstructive pulmonary disease (AECOPD) result in considerable morbidity and mortality. However, there are no objective biomarkers to diagnose AECOPD. METHODS: We used multiple reaction monitoring mass spectrometry to quantify 129 distinct proteins in plasma...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Leung, Janice M., Chen, Virginia, Hollander, Zsuzsanna, Dai, Darlene, Tebbutt, Scott J., Aaron, Shawn D., Vandemheen, Kathy L., Rennard, Stephen I., FitzGerald, J. Mark, Woodruff, Prescott G., Lazarus, Stephen C., Connett, John E., Coxson, Harvey O., Miller, Bruce, Borchers, Christoph, McManus, Bruce M., Ng, Raymond T., Sin, Don D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4985129/
https://ncbi.nlm.nih.gov/pubmed/27525416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0161129
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