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Calcium Dynamics of Ex Vivo Long-Term Cultured CD8(+) T Cells Are Regulated by Changes in Redox Metabolism
T cells reach a state of replicative senescence characterized by a decreased ability to proliferate and respond to foreign antigens. Calcium release associated with TCR engagement is widely used as a surrogate measure of T cell response. Using an ex vivo culture model that partially replicates featu...
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| Vydáno v: | PLoS One |
|---|---|
| Hlavní autoři: | , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Public Library of Science
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4985122/ https://ncbi.nlm.nih.gov/pubmed/27526200 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0159248 |
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