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A soluble activator that favors the ex vivo expansion of CD8(+)CD27(+) T cells

Adoptive cell therapy involves the infusion of tumor-reactive T cells into patients with cancer to provide antitumor immunity. The ex vivo expansion and differentiation of such T cells are key parameters that affect their therapeutic potential. Human T cells are presently expanded in culture through...

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Vydáno v:JCI Insight
Hlavní autoři: Matus, Esther I., Sparkes, Amanda, Gariépy, Jean
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7710272/
https://ncbi.nlm.nih.gov/pubmed/33208551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.141293
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