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A soluble activator that favors the ex vivo expansion of CD8(+)CD27(+) T cells
Adoptive cell therapy involves the infusion of tumor-reactive T cells into patients with cancer to provide antitumor immunity. The ex vivo expansion and differentiation of such T cells are key parameters that affect their therapeutic potential. Human T cells are presently expanded in culture through...
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| Publié dans: | JCI Insight |
|---|---|
| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7710272/ https://ncbi.nlm.nih.gov/pubmed/33208551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/jci.insight.141293 |
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