Loss of the cell polarity determinant human Discs-large is a novel molecular marker of nodal involvement and poor prognosis in endometrial cancer

BACKGROUND: Recent Drosophila studies showed that Discs-large (Dlg) is critical for regulation of cell polarity and tissue architecture. We investigated the possibility that loss of the human homologue of Drosophila Dlg (DLG1) is involved in endometrial carcinogenesis. METHODS: We analysed DLG1 expr...

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Bibliografische gegevens
Gepubliceerd in:Br J Cancer
Hoofdauteurs: Sugihara, Takeru, Nakagawa, Shunsuke, Sasajima, Yuko, Ichinose, Takayuki, Hiraike, Haruko, Kondo, Fukuo, Uozaki, Hiroshi, Fukusato, Toshio, Ayabe, Takuya
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2016
Onderwerpen:
Molecular Diagnostics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984904/
https://ncbi.nlm.nih.gov/pubmed/27002939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.24
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