Loss of the cell polarity determinant human Discs-large is a novel molecular marker of nodal involvement and poor prognosis in endometrial cancer

BACKGROUND: Recent Drosophila studies showed that Discs-large (Dlg) is critical for regulation of cell polarity and tissue architecture. We investigated the possibility that loss of the human homologue of Drosophila Dlg (DLG1) is involved in endometrial carcinogenesis. METHODS: We analysed DLG1 expr...

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Опубликовано в: :Br J Cancer
Главные авторы: Sugihara, Takeru, Nakagawa, Shunsuke, Sasajima, Yuko, Ichinose, Takayuki, Hiraike, Haruko, Kondo, Fukuo, Uozaki, Hiroshi, Fukusato, Toshio, Ayabe, Takuya
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group 2016
Предметы:
Molecular Diagnostics
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984904/
https://ncbi.nlm.nih.gov/pubmed/27002939
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.24
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