Nanoparticle-Based Topical Ophthalmic Gel Formulation for Sustained Release of Hydrocortisone Butyrate

This study was conducted to develop formulations of hydrocortisone butyrate (HB)-loaded poly(d,l-lactic-co-glycolic acid) nanoparticles (PLGA NP) suspended in thermosensitive gel to improve ocular bioavailability of HB for the treatment of bacterial corneal keratitis. PLGA NP with different surfacta...

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Vydáno v:AAPS PharmSciTech
Hlavní autoři: Yang, Xiaoyan, Trinh, Hoang M., Agrahari, Vibhuti, Sheng, Ye, Pal, Dhananjay, Mitra, Ashim K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984892/
https://ncbi.nlm.nih.gov/pubmed/26085051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0354-5
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