Nanomicellar Topical Aqueous Drop Formulation of Rapamycin for Back-of-the-Eye Delivery

The objective of this study was to develop a clear, aqueous rapamycin-loaded mixed nanomicellar formulations (MNFs) for the back-of-the-eye delivery. MNF of rapamycin (0.2%) was prepared with vitamin E tocopherol polyethylene glycol succinate (TPGS) (Vit E TPGS) and octoxynol-40 (Oc-40) as polymeric...

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Vydáno v:AAPS PharmSciTech
Hlavní autoři: Cholkar, Kishore, Gunda, Sriram, Earla, Ravinder, Pal, Dhananjay, Mitra, Ashim K.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer US 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444623/
https://ncbi.nlm.nih.gov/pubmed/25425389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0244-2
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