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Nanomicellar Topical Aqueous Drop Formulation of Rapamycin for Back-of-the-Eye Delivery

The objective of this study was to develop a clear, aqueous rapamycin-loaded mixed nanomicellar formulations (MNFs) for the back-of-the-eye delivery. MNF of rapamycin (0.2%) was prepared with vitamin E tocopherol polyethylene glycol succinate (TPGS) (Vit E TPGS) and octoxynol-40 (Oc-40) as polymeric...

詳細記述

保存先:
書誌詳細
出版年:AAPS PharmSciTech
主要な著者: Cholkar, Kishore, Gunda, Sriram, Earla, Ravinder, Pal, Dhananjay, Mitra, Ashim K.
フォーマット: Artigo
言語:Inglês
出版事項: Springer US 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4444623/
https://ncbi.nlm.nih.gov/pubmed/25425389
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-014-0244-2
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