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Topical, Aqueous, Clear Cyclosporine Formulation Design for Anterior and Posterior Ocular Delivery

PURPOSE: The main objective of this study was to optimize cyclosporine (CsA) nanomicellar solution and study in vivo ocular CsA tissue distribution with a topical drop. METHODS: An optimized blend of hydrogenated castor oil-40 and octoxynol-40 was prepared to entrap CsA within nanomicelles. In vivo...

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Bibliografski detalji
Izdano u:Transl Vis Sci Technol
Glavni autori: Cholkar, Kishore, Gilger, Brian C., Mitra, Ashim K.
Format: Artigo
Jezik:Inglês
Izdano: The Association for Research in Vision and Ophthalmology 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4418434/
https://ncbi.nlm.nih.gov/pubmed/25964868
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/tvst.4.3.1
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