Population genetic differentiation of height and body mass index across Europe

Across-nation differences in the mean of complex traits such as obesity and stature are common(1–8), but the reasons for these differences are not known. Here, we find evidence that many independent loci of small effect combine to create population genetic differences in height and body mass index (...

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Pubblicato in:Nat Genet
Autori principali: Robinson, Matthew R., Hemani, Gibran, Medina-Gomez, Carolina, Mezzavilla, Massimo, Esko, Tonu, Shakhbazov, Konstantin, Powell, Joseph E., Vinkhuyzen, Anna, Berndt, Sonja I., Gustafsson, Stefan, Justice, Anne E., Kahali, Bratati, Locke, Adam E., Pers, Tune H., Vedantam, Sailaja, Wood, Andrew R., van Rheenen, Wouter, Andreassen, Ole A., Gasparini, Paolo, Metspalu, Andres, van den Berg, Leonard H., Veldink, Jan H., Rivadeneira, Fernando, Werge, Thomas M., Abecasis, Goncalo R., Boomsma, Dorret I., Chasman, Daniel I., de Geus, Eco J.C., Frayling, Timothy M., Hirschhorn, Joel N., Hottenga, Jouke Jan, Ingelsson, Erik, Loos, Ruth J.F., Magnusson, Patrik K. E., Martin, Nicholas G., Montgomery, Grant W., North, Kari E., Pedersen, Nancy L., Spector, Timothy D., Speliotes, Elizabeth K., Goddard, Michael E., Yang, Jian, Visscher, Peter M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984852/
https://ncbi.nlm.nih.gov/pubmed/26366552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ng.3401
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