Antitumour activity of the novel flavonoid Oncamex in preclinical breast cancer models

BACKGROUND: The natural polyphenol myricetin induces cell cycle arrest and apoptosis in preclinical cancer models. We hypothesised that myricetin-derived flavonoids with enhanced redox properties, improved cell uptake and mitochondrial targeting might have increased potential as antitumour agents. M...

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Bibliografiska uppgifter
I publikationen:Br J Cancer
Huvudupphovsmän: Martínez-Pérez, Carlos, Ward, Carol, Turnbull, Arran K, Mullen, Peter, Cook, Graeme, Meehan, James, Jarman, Edward J, Thomson, Patrick IT, Campbell, Colin J, McPhail, Donald, Harrison, David J, Langdon, Simon P
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group 2016
Ämnen:
Translational Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984802/
https://ncbi.nlm.nih.gov/pubmed/27031849
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2016.6
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