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Notwithstanding Circumstantial Alibis, Cytotoxic T Cells Can Be Major Killers of HIV-1-Infected Cells

Several experiments suggest that in the chronic phase of human immunodeficiency virus type 1 (HIV-1) infection, CD8(+) cytotoxic T lymphocytes (CTL) contribute very little to the death of productively infected cells. First, the expected life span of productively infected cells is fairly long, i.e.,...

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Publicado en:J Virol
Main Authors: Gadhamsetty, Saikrishna, Coorens, Tim, de Boer, Rob J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984658/
https://ncbi.nlm.nih.gov/pubmed/27226367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00306-16
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