Site-directed mutagenesis of histidine residues involved in Cu(II) binding and reduction by sperm whale myoglobin.
Sperm whale myoglobin (Mb) reduces Cu(II) through a site-specific mechanism involving complexation by one or more surface histidine residues. Three mutants of Mb, derived from recombinant wild-type Mb, were designed in which surface histidine residues exhibiting strong Cu(II) binding were replaced w...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1992
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC49846/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1518828/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.89.17.8016 |
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