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Use of site-directed mutagenesis to probe structure-function relationships of alpha-toxin from Clostridium perfringens.

The NH2-terminal domain of the alpha-toxin of Clostridium perfringens is highly homologous to the complete phospholipase C from Bacillus cereus (PC-PLC), for which a high-resolution crystal structure is available. This structural information was used as the basis of a site-directed mutagenesis strat...

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Detalhes bibliográficos
Publicado no:Infect Immun
Principais autores: Guillouard, I, Garnier, T, Cole, S T
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174095/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8698464/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.7.2440-2444.1996
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