Use of site-directed mutagenesis to probe structure-function relationships of alpha-toxin from Clostridium perfringens.
The NH2-terminal domain of the alpha-toxin of Clostridium perfringens is highly homologous to the complete phospholipase C from Bacillus cereus (PC-PLC), for which a high-resolution crystal structure is available. This structural information was used as the basis of a site-directed mutagenesis strat...
Guardat en:
| Publicat a: | Infect Immun |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC174095/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8698464/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.64.7.2440-2444.1996 |
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