Modulating mitochondrial quality in disease transmission: towards enabling mitochondrial DNA disease carriers to have healthy children

One in 400 people has a maternally inherited mutation in mtDNA potentially causing incurable disease. In so-called heteroplasmic disease, mutant and normal mtDNA co-exist in the cells of carrier women. Disease severity depends on the proportion of inherited abnormal mtDNA molecules. Families who hav...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Biochem Soc Trans
Main Authors: Diot, Alan, Dombi, Eszter, Lodge, Tiffany, Liao, Chunyan, Morten, Karl, Carver, Janet, Wells, Dagan, Child, Tim, Johnston, Iain G., Williams, Suzannah, Poulton, Joanna
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2016
Assuntos:
Biochemical Society Focused Meetings
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4984448/
https://ncbi.nlm.nih.gov/pubmed/27528757
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BST20160095
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados