Re-silencing of silent synapses unmasks anti-relapse effects of environmental enrichment

Environmental enrichment (EE) has long been postulated as a behavioral treatment for drug addiction based on its preventive effects in animal models: rodents experiencing prior EE exhibit increased resistance to establishing drug taking and seeking. However, the therapeutic effects of EE, namely, th...

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Bibliographic Details
Published in:Proc Natl Acad Sci U S A
Main Authors: Ma, Yao-Ying, Wang, Xiusong, Huang, Yanhua, Marie, Helene, Nestler, Eric J., Schlüter, Oliver M., Dong, Yan
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2016
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983865/
https://ncbi.nlm.nih.gov/pubmed/27091967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1524739113
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