Llwytho...
NF-κB–driven suppression of FOXO3a contributes to EGFR mutation-independent gefitinib resistance
Therapy with epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors (EGFR-TKIs, such as gefitinib or erlotinib) significantly prolongs survival time for patients with tumors harboring an activated mutation on EGFR; however, up to 40% of lung cancer patients exhibit acquired resistance to...
Wedi'i Gadw mewn:
| Cyhoeddwyd yn: | Proc Natl Acad Sci U S A |
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| Prif Awduron: | , , , , , , , , , , , , |
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
National Academy of Sciences
2016
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| Pynciau: | |
| Mynediad Ar-lein: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4983816/ https://ncbi.nlm.nih.gov/pubmed/27091996 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1522612113 |
| Tagiau: |
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