Antibiotic treatment enhances the genome-wide mutation rate of target cells

Although it is well known that microbial populations can respond adaptively to challenges from antibiotics, empirical difficulties in distinguishing the roles of de novo mutation and natural selection have left several issues unresolved. Here, we explore the mutational properties of Escherichia coli...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Long, Hongan, Miller, Samuel F., Strauss, Chloe, Zhao, Chaoxian, Cheng, Lei, Ye, Zhiqiang, Griffin, Katherine, Te, Ronald, Lee, Heewook, Chen, Chi-Chun, Lynch, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2016
Konular:
PNAS Plus
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983809/
https://ncbi.nlm.nih.gov/pubmed/27091991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1601208113
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