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mGlu5, Dopamine D(2) and Adenosine A(2A) Receptors in L-DOPA-induced Dyskinesias

Patients with Parkinson’s disease (PD) receiving L-3,4-dihydroxyphenylalanine (L-DOPA, the gold-standard treatment for this disease) frequently develop abnormal involuntary movements, termed L-DOPA-induced dyskinesias (LID). Glutamate overactivity is well documented in PD and LID. An approach to man...

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Dettagli Bibliografici
Pubblicato in:Curr Neuropharmacol
Autori principali: Morin, Nicolas, Morissette, Marc, Grégoire, Laurent, Di Paolo, Thérèse
Natura: Artigo
Lingua:Inglês
Pubblicazione: Bentham Science Publishers 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983750/
https://ncbi.nlm.nih.gov/pubmed/26639458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2174/1570159X14666151201185652
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