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Erythropoietin increases macrophage-mediated T cell suppression

Erythropoietin (EPO), used to treat anemia in cancer patients, has been reported to accelerate tumor progression and increase mortality. Research of the mechanism for this effect has focused upon EPOR expression by tumor cells. We model the high macrophage to lymphocyte ratio found in tumor microenv...

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Detalhes bibliográficos
Publicado no:Cell Immunol
Main Authors: Wood, Michelle A., Goldman, Naomi, DePierri, Kelley, Somerville, John, Riggs, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4983461/
https://ncbi.nlm.nih.gov/pubmed/27262376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellimm.2016.05.004
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