CD28 ligation increases macrophage suppression of T-cell proliferation

When compared to spleen or lymph node cells, resident peritoneal cavity cells respond poorly to T-cell activation in vitro. The greater proportional representation of macrophages in this cell source has been shown to actively suppress the T-cell response. Peritoneal macrophages exhibit an immature p...

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Detalhes bibliográficos
Main Authors: Silberman, Daniel, Bucknum, Amanda, Bartlett, Thomas, Composto, Gabriella, Kozlowski, Megan, Walker, Amanda, Werda, Amy, Cua, Jackelyn, Sharpe, Arlene H, Somerville, John E, Riggs, James E
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3389597/
https://ncbi.nlm.nih.gov/pubmed/22522653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cmi.2012.13
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